Despite vs In Spite Of
Use Of Despite And In Spite Of
They both are prepositional phrases followed by a noun / pronoun or V-ing form.
Despite the harsh weather conditions, the climbers managed to return from Everest.
In spite of the devastating effects of the earthquake, the city is expected to grow.
Contrary to popular belief, there is no difference between these two; neither in meaning nor in usage. You can substitute despite for in spite of and vise verse.
Despite / in spite of
having a newborn baby, Sally has never missed any opportunity to go on vacation.
Be careful not to use
because it's incorrect.
We say despite the wind, despite the bad news... and not
despite of the wind
It's either in spite of
Don't confuse these two structures with "although" as although is followed by a subordinating clause and not a prepositional phrase.
Although she has
a newborn baby, Sally has never missed any opportunity to go on vacation.